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Rick Stewart didn't understand about the laburnum trees growing in Bulgaria and their prospective to produce a drug for giving up smoking back when he was the primary executive of the pharmaceutical business Amarin. He was unfathomable inside the drug industry, a place typically criticized for its short-sighted focus on revenues.


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Just then might he spot the chance in those yellow-flowering trees. Now, with the aid of the National Institutes of Health, Stewart is trying to introduce the laburnum-derived drug to the U.S. market. The pill works by disrupting tobacco cravings, much like Pfizer's top-selling Chantix, but perhaps without that drug's prominent negative effects and at a much lower cost.


Today, scientists are delighted about what could be the first new treatment for smoking cigarettes cessation to emerge in years. "We need this," said David Shurtleff, deputy director of the NIH Center for Complementary and Integrative Health, describing why his agency is helping to get the drug authorized. But laburnum's pledge is not brand-new.


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From left, Ronald Martell, Rick Stewart and Anthony Clarke of Extab. Stewart wishes to rebrand the smoking-cessation drug Tabex as Extab for sale in Western European and U.S. markets. ( cytisine reddit ) In 2007, Stewart had staked his task as the head of Amarin on a various drug. Miraxion was for treating Huntington's Disease, and early on it revealed indications of improving signs of the neurological condition.


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Financiers in Amarin, a $240 million company based in New Jersey, were shocked. The company's stock fell 80 percent. Stewart was out of a task. "The CEO constantly falls on his sword," Stewart, 56, says now. But Miraxion did appear to assist patients with Huntington's it just took longer than the six months allocated throughout the medical trials.



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This led Stewart and Anthony Clarke, who likewise lost his job after running the trials for Amarin, to wonder what other misunderstood drugs were out there. They went on a hunt. "These drugs are uncared for or unwanted. They need tlc," Stewart states. "And pharma, for whatever reason, can't be troubled with them." They set up a tiny company outside London named Ricanto a mash-up of their given names.